2022 Big 12 Conference Leaders Rushing Defense - Games in August/September Only through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Iowa State | 4 | 111 | 303 | 2.73 | 2 | 27.75 | 75.75 |
| 2 | Baylor | 4 | 124 | 318 | 2.56 | 2 | 31.00 | 79.50 |
| 3 | West Virginia | 4 | 124 | 393 | 3.17 | 7 | 31.00 | 98.25 |
| 4 | Texas Tech | 4 | 137 | 399 | 2.91 | 4 | 34.25 | 99.75 |
| 5 | TCU | 3 | 94 | 302 | 3.21 | 4 | 31.33 | 100.67 |
| 6 | Oklahoma State | 3 | 107 | 334 | 3.12 | 3 | 35.67 | 111.33 |
| 7 | Texas | 4 | 153 | 540 | 3.53 | 5 | 38.25 | 135.00 |
| 8 | Kansas | 4 | 155 | 552 | 3.56 | 7 | 38.75 | 138.00 |
| 9 | Kansas State | 4 | 144 | 605 | 4.20 | 2 | 36.00 | 151.25 |
| 10 | Oklahoma | 4 | 177 | 630 | 3.56 | 6 | 44.25 | 157.50 |