2022 Big 12 Conference Leaders Passing Defense - Games in August/September Only through 01/09/2023
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Kansas State | 4 | 130 | 72 | 55.4 | 773 | 5.9 | 5 | 7 | 107.26 | 32.5 | 193.3 |
| 2 | Iowa State | 4 | 131 | 73 | 55.7 | 761 | 5.8 | 5 | 4 | 111.02 | 32.8 | 190.3 |
| 3 | Oklahoma | 4 | 137 | 84 | 61.3 | 817 | 6.0 | 2 | 3 | 111.85 | 34.3 | 204.3 |
| 4 | TCU | 3 | 116 | 64 | 55.2 | 817 | 7.0 | 4 | 4 | 118.81 | 38.7 | 272.3 |
| 5 | Baylor | 4 | 142 | 84 | 59.2 | 903 | 6.4 | 6 | 2 | 123.70 | 35.5 | 225.8 |
| 6 | Texas | 4 | 157 | 106 | 67.5 | 980 | 6.2 | 4 | 2 | 125.81 | 39.3 | 245.0 |
| 7 | West Virginia | 4 | 111 | 60 | 54.1 | 818 | 7.4 | 5 | 1 | 129.02 | 27.8 | 204.5 |
| 8 | Oklahoma State | 3 | 114 | 64 | 56.1 | 796 | 7.0 | 6 | 1 | 130.41 | 38.0 | 265.3 |
| 9 | Texas Tech | 4 | 116 | 65 | 56.0 | 910 | 7.8 | 5 | 2 | 132.70 | 29.0 | 227.5 |
| 10 | Kansas | 4 | 132 | 88 | 66.7 | 1058 | 8.0 | 6 | 3 | 144.45 | 33.0 | 264.5 |