2022 Atlantic Coast Conference Leaders Rushing Defense - Games vs. Conference Teams Only through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 8 | 237 | 752 | 3.17 | 5 | 29.63 | 94.00 |
| 2 | Clemson | 9 | 272 | 865 | 3.18 | 6 | 30.22 | 96.11 |
| 3 | Duke | 8 | 247 | 882 | 3.57 | 5 | 30.88 | 110.25 |
| 4 | North Carolina State | 8 | 249 | 906 | 3.64 | 10 | 31.13 | 113.25 |
| 5 | Wake Forest | 8 | 272 | 1054 | 3.88 | 10 | 34.00 | 131.75 |
| 6 | North Carolina | 9 | 306 | 1238 | 4.05 | 20 | 34.00 | 137.56 |
| 7 | Louisville | 8 | 297 | 1132 | 3.81 | 10 | 37.13 | 141.50 |
| 8 | Florida State | 8 | 313 | 1154 | 3.69 | 7 | 39.13 | 144.25 |
| 9 | Virginia Tech | 7 | 249 | 1032 | 4.14 | 11 | 35.57 | 147.43 |
| 10 | Virginia | 7 | 295 | 1075 | 3.64 | 11 | 42.14 | 153.57 |
| 11 | Georgia Tech | 8 | 301 | 1287 | 4.28 | 11 | 37.63 | 160.88 |
| 12 | Boston College | 8 | 310 | 1320 | 4.26 | 18 | 38.75 | 165.00 |
| 13 | Miami (Florida) | 8 | 306 | 1365 | 4.46 | 15 | 38.25 | 170.63 |
| 14 | Syracuse | 8 | 334 | 1366 | 4.09 | 11 | 41.75 | 170.75 |