2022 Atlantic Coast Conference Leaders Opponent First Downs - Games vs. FBS Teams With Winning Record Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 6 | 31 | 66 | 10 | 107 | 17.8 |
| 2 | North Carolina State | 9 | 53 | 99 | 19 | 171 | 19.0 |
| 3 | Louisville | 10 | 96 | 78 | 19 | 193 | 19.3 |
| 4 | Miami (Florida) | 7 | 64 | 66 | 8 | 138 | 19.7 |
| 5 | Florida State | 6 | 56 | 55 | 13 | 124 | 20.7 |
| 6 | Clemson | 9 | 71 | 100 | 21 | 192 | 21.3 |
| 7 | Virginia Tech | 5 | 43 | 59 | 7 | 109 | 21.8 |
| 8 | Syracuse | 9 | 96 | 90 | 12 | 198 | 22.0 |
| 9 | North Carolina | 7 | 61 | 79 | 15 | 155 | 22.1 |
| 10 | Boston College | 8 | 75 | 85 | 18 | 178 | 22.3 |
| 11 | Virginia | 6 | 59 | 66 | 14 | 139 | 23.2 |
| 12 | Duke | 4 | 36 | 54 | 3 | 93 | 23.3 |
| 12 | Georgia Tech | 8 | 91 | 75 | 20 | 186 | 23.3 |
| 14 | Wake Forest | 8 | 67 | 110 | 11 | 188 | 23.5 |