2022 Atlantic Coast Conference Leaders Rushing Defense - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Virginia Tech | 8 | 295 | 1250 | 4.24 | 12 | 36.88 | 156.25 |
| 2 | North Carolina State | 10 | 316 | 1036 | 3.28 | 11 | 31.60 | 103.60 |
| 3 | Duke | 10 | 320 | 1162 | 3.63 | 7 | 32.00 | 116.20 |
| 4 | Pittsburgh | 11 | 333 | 1161 | 3.49 | 11 | 30.27 | 105.55 |
| 5 | North Carolina | 10 | 338 | 1447 | 4.28 | 22 | 33.80 | 144.70 |
| 5 | Miami (Florida) | 9 | 338 | 1489 | 4.41 | 16 | 37.56 | 165.44 |
| 7 | Wake Forest | 10 | 339 | 1281 | 3.78 | 12 | 33.90 | 128.10 |
| 7 | Louisville | 9 | 339 | 1290 | 3.81 | 10 | 37.67 | 143.33 |
| 9 | Virginia | 8 | 340 | 1273 | 3.74 | 11 | 42.50 | 159.13 |
| 10 | Clemson | 11 | 341 | 1044 | 3.06 | 9 | 31.00 | 94.91 |
| 11 | Boston College | 9 | 352 | 1532 | 4.35 | 21 | 39.11 | 170.22 |
| 12 | Syracuse | 10 | 388 | 1504 | 3.88 | 13 | 38.80 | 150.40 |
| 13 | Georgia Tech | 10 | 404 | 1867 | 4.62 | 19 | 40.40 | 186.70 |
| 14 | Florida State | 11 | 449 | 1808 | 4.03 | 13 | 40.82 | 164.36 |