2022 Atlantic Coast Conference Leaders Interceptions - Games vs. Conference Teams Only through 01/09/2023
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Louisville | 8 | 12 | 252 | 2 | 1.50 |
| 2 | Pittsburgh | 8 | 6 | 124 | 2 | 0.75 |
| 3 | Clemson | 9 | 7 | 105 | 1 | 0.78 |
| 4 | Miami (Florida) | 8 | 9 | 104 | 1 | 1.13 |
| 5 | Duke | 8 | 8 | 93 | 1 | 1.00 |
| 6 | North Carolina State | 8 | 10 | 59 | 0 | 1.25 |
| 7 | North Carolina | 9 | 6 | 40 | 0 | 0.67 |
| 7 | Virginia | 7 | 4 | 40 | 0 | 0.57 |
| 9 | Virginia Tech | 7 | 4 | 38 | 1 | 0.57 |
| 10 | Wake Forest | 8 | 2 | 36 | 1 | 0.25 |
| 11 | Syracuse | 8 | 7 | 35 | 0 | 0.88 |
| 12 | Georgia Tech | 8 | 6 | 30 | 1 | 0.75 |
| 13 | Florida State | 8 | 7 | 10 | 0 | 0.88 |
| 14 | Boston College | 8 | 4 | 0 | 0 | 0.50 |