2022 Atlantic Coast Conference Leaders First Downs - Games in August/September Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Miami (Florida) | 4 | 46 | 52 | 10 | 108 | 27.0 |
| 1 | Wake Forest | 4 | 26 | 52 | 11 | 89 | 22.3 |
| 3 | North Carolina | 4 | 39 | 50 | 10 | 99 | 24.8 |
| 4 | Syracuse | 4 | 36 | 48 | 12 | 96 | 24.0 |
| 5 | North Carolina State | 4 | 40 | 47 | 7 | 94 | 23.5 |
| 5 | Virginia Tech | 4 | 21 | 47 | 8 | 76 | 19.0 |
| 7 | Clemson | 4 | 41 | 45 | 8 | 94 | 23.5 |
| 8 | Florida State | 4 | 49 | 43 | 5 | 97 | 24.3 |
| 9 | Duke | 4 | 38 | 42 | 9 | 89 | 22.3 |
| 9 | Louisville | 4 | 39 | 42 | 6 | 87 | 21.8 |
| 11 | Boston College | 4 | 21 | 40 | 8 | 69 | 17.3 |
| 12 | Pittsburgh | 4 | 46 | 37 | 5 | 88 | 22.0 |
| 13 | Virginia | 4 | 35 | 35 | 14 | 84 | 21.0 |
| 14 | Georgia Tech | 4 | 26 | 34 | 3 | 63 | 15.8 |