2022 Atlantic Coast Conference Leaders First Downs - Games in October Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Wake Forest | 4 | 43 | 60 | 9 | 112 | 28.0 |
| 2 | North Carolina | 4 | 31 | 66 | 5 | 102 | 25.5 |
| 3 | Florida State | 4 | 41 | 46 | 9 | 96 | 24.0 |
| 4 | Duke | 4 | 45 | 31 | 11 | 87 | 21.8 |
| 4 | Miami (Florida) | 4 | 26 | 53 | 8 | 87 | 21.8 |
| 6 | Clemson | 4 | 42 | 32 | 10 | 84 | 21.0 |
| 7 | Pittsburgh | 4 | 41 | 35 | 6 | 82 | 20.5 |
| 8 | Louisville | 4 | 33 | 39 | 8 | 80 | 20.0 |
| 9 | Syracuse | 4 | 33 | 42 | 3 | 78 | 19.5 |
| 10 | North Carolina State | 4 | 27 | 40 | 9 | 76 | 19.0 |
| 11 | Georgia Tech | 4 | 28 | 35 | 7 | 70 | 17.5 |
| 12 | Virginia | 4 | 23 | 37 | 8 | 68 | 17.0 |
| 13 | Virginia Tech | 4 | 22 | 30 | 12 | 64 | 16.0 |
| 14 | Boston College | 4 | 24 | 37 | 2 | 63 | 15.8 |