2022 American Athletic Conference Leaders Interceptions - Games vs. Conference Teams Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Malik Fleming | ECU | JR | CB | 8 | 3 | 49 | 0 | 0.38 |
| 2 | Quindell Johnson | Memphis | SR | DB | 7 | 2 | 4 | 0 | 0.29 |
| 3 | Nick Roberts | SMU | SR | S | 8 | 2 | 61 | 0 | 0.25 |
| 3 | Jahari Rogers | SMU | SO | CB | 8 | 2 | 20 | 0 | 0.25 |
| 3 | Divaad Wilson | UCF | SR | DB | 8 | 2 | 12 | 0 | 0.25 |
| 3 | Jireh Wilson | ECU | JR | SAF | 8 | 2 | 3 | 0 | 0.25 |
| 3 | Elias Larry | Navy | SO | CB | 8 | 2 | 3 | 0 | 0.25 |
| 3 | Tyler Murray | Memphis | SR | LB | 8 | 2 | 0 | 0 | 0.25 |
| 9 | Davonte Brown | UCF | JR | CB | 9 | 2 | 22 | 0 | 0.22 |
| 9 | Larry Brooks | Tulane | SR | S | 9 | 2 | 7 | 0 | 0.22 |
| 11 | Jayce Rogers | Houston | SR | DB | 7 | 1 | 28 | 0 | 0.14 |
| 11 | Art Green | Houston | SR | DB | 7 | 1 | 28 | 0 | 0.14 |
| 11 | Gerard Stringer | ECU | SR | SAF | 7 | 1 | 10 | 0 | 0.14 |
| 11 | Jacob Dingle | Cincinnati | SR | S | 7 | 1 | 0 | 0 | 0.14 |
| 11 | Davion Ross | Memphis | JR | DB | 7 | 1 | 0 | 0 | 0.14 |
| 11 | Aamaris Brown | S Florida | FR | DB | 7 | 1 | 0 | 0 | 0.14 |
| 11 | Matthew Hill | S Florida | JR | S | 7 | 1 | 0 | 0 | 0.14 |
| 11 | Brandon Crossley | SMU | SR | S | 7 | 1 | 0 | 0 | 0.14 |
| 11 | Isaac Slade-Matautia | SMU | SR | LB | 7 | 1 | -3 | 0 | 0.14 |
| 20 | Sylvonta Oliver | Memphis | SR | DB | 8 | 1 | 71 | 0 | 0.13 |
| 20 | Julius Wood | ECU | JR | SAF | 8 | 1 | 47 | 1 | 0.13 |
| 20 | Layton Jordan | Temple | JR | OLB | 8 | 1 | 35 | 1 | 0.13 |
| 20 | Muheem McCargo | Temple | SO | SAF | 8 | 1 | 35 | 0 | 0.13 |
| 20 | Mbiti Williams Jr. | Navy | SO | CB | 8 | 1 | 31 | 0 | 0.13 |
| 20 | Kendarin Ray | Tulsa | SR | S | 8 | 1 | 23 | 0 | 0.13 |
| 20 | Xavier Cullens | Memphis | SR | LB | 8 | 1 | 22 | 0 | 0.13 |
| 20 | Deshawn Pace | Cincinnati | JR | LB | 8 | 1 | 18 | 1 | 0.13 |
| 20 | Nicholas Straw | Navy | SR | RDR | 8 | 1 | 18 | 0 | 0.13 |
| 20 | Arquon Bush | Cincinnati | SR | CB | 8 | 1 | 15 | 0 | 0.13 |
| 20 | Cincir Evans | Memphis | SR | LB | 8 | 1 | 15 | 0 | 0.13 |
| 20 | Justin Wright | Tulsa | SR | LB | 8 | 1 | 5 | 0 | 0.13 |
| 20 | Colin Ramos | Navy | SO | LB | 8 | 1 | 5 | 0 | 0.13 |
| 20 | Jalen McMurray | Temple | FR | CB | 8 | 1 | 4 | 0 | 0.13 |
| 20 | Juan Powell | ECU | SO | CB | 8 | 1 | 2 | 0 | 0.13 |
| 20 | Ja'Von Hicks | Cincinnati | SR | S | 8 | 1 | 0 | 0 | 0.13 |
| 20 | Bryon Threats | Cincinnati | SO | S | 8 | 1 | 0 | 0 | 0.13 |
| 20 | Alex Odom | Temple | SO | SAF | 8 | 1 | 0 | 0 | 0.13 |
| 20 | Tyon Davis | Tulsa | SR | CB | 8 | 1 | 0 | 0 | 0.13 |
| 20 | Tyler Fletcher | Navy | SO | LB | 8 | 1 | 0 | 0 | 0.13 |
| 40 | Macon Clark | Tulane | SR | S | 9 | 1 | 6 | 0 | 0.11 |
| 40 | Lummie Young IV | Tulane | SR | S | 9 | 1 | 6 | 0 | 0.11 |
| 40 | Justin Hodges | UCF | JR | DB | 9 | 1 | 0 | 0 | 0.11 |
| 40 | DJ Douglas | Tulane | SO | DB | 9 | 1 | 0 | 0 | 0.11 |
| 40 | Dorian Williams | Tulane | SR | LB | 9 | 1 | 0 | 0 | 0.11 |
| 40 | Jarius Monroe | Tulane | JR | DB | 9 | 1 | 0 | 0 | 0.11 |
Note: To qualify, player must have played in 75% of his team's games.