2022 American Athletic Conference Leaders Long All Purpose Plays - Games vs. Non-Conference Teams Only through 01/09/2023
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Brian Battie | S Florida | SO | RB | 4 | 4 | 3 | 2 | 1 | 0 | 0 | 0 |
| 1 | Keaton Mitchell | ECU | SO | RB | 5 | 7 | 4 | 2 | 1 | 1 | 1 | 0 |
| 3 | Javon Baker | UCF | JR | WR | 5 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Xavier Cullens | Memphis | SR | LB | 5 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Roderick Daniels, Jr. | SMU | SO | WR | 5 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Nathaniel Dell | Houston | JR | WR | 5 | 4 | 2 | 1 | 1 | 0 | 0 | 0 |
| 3 | Jevyon Ducker | Memphis | SO | RB | 5 | 4 | 3 | 1 | 0 | 0 | 0 | 0 |
| 3 | Isaiah Epps | Tulsa | SR | WR | 4 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Daba Fofana | Navy | SO | FB | 4 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Anton Hall Jr. | Navy | SO | FB | 4 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Jsi Hatfield | ECU | JR | WR | 2 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Alec Holler | UCF | SR | TE | 5 | 2 | 1 | 1 | 1 | 0 | 0 | 0 |
| 3 | Jimmy Horn Jr. | S Florida | SO | WR | 3 | 2 | 1 | 1 | 1 | 1 | 1 | 0 |
| 3 | Jha'Quan Jackson | Tulane | JR | WR | 5 | 5 | 3 | 1 | 1 | 1 | 1 | 0 |
| 3 | Jordan Kerley | SMU | JR | WR | 4 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Eddie Lewis | Memphis | SR | WR | 5 | 3 | 2 | 1 | 1 | 0 | 0 | 0 |
| 3 | RJ Maryland | SMU | FR | TE | 5 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | TJ McDaniel | SMU | SO | RB | 5 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Myles Montgomery | Cincinnati | FR | RB | 5 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Tre'Mon Morris-Brash | UCF | SR | DE | 5 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 3 | Rashee Rice | SMU | SR | WR | 4 | 4 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Johnny Richardson | UCF | JR | RB | 5 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Gabriel Rogers | Memphis | SR | WR | 5 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Jayce Rogers | Houston | SR | DB | 5 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Adonicas Sanders | Temple | SR | WR | 4 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | JuanCarlos Santana | Tulsa | SR | WR | 4 | 5 | 3 | 1 | 0 | 0 | 0 | 0 |
| 3 | Joseph Scates | Memphis | JR | WR | 4 | 2 | 2 | 1 | 0 | 0 | 0 | 0 |
| 3 | Tyler Scott | Cincinnati | JR | WR | 4 | 5 | 2 | 1 | 1 | 1 | 0 | 0 |
| 3 | Tyjae Spears | Tulane | JR | RB | 5 | 4 | 2 | 1 | 1 | 0 | 0 | 0 |
| 3 | Duece Watts | Tulane | SR | WR | 5 | 2 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Xavier Weaver | S Florida | JR | WR | 3 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 3 | Shae Wyatt | Tulane | SR | WR | 5 | 2 | 2 | 1 | 1 | 1 | 0 | 0 |