2022 American Athletic Conference Leaders Passes Defended - Games in December/January Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Jarius Monroe | Tulane | JR | DB | 2 | 1 | 2 | 3 | 1.50 |
| 2 | Sylvonta Oliver | Memphis | SR | DB | 1 | 2 | 0 | 2 | 2.00 |
| 2 | Jayce Rogers | Houston | SR | DB | 1 | 1 | 1 | 2 | 2.00 |
| 2 | Justin Hodges | UCF | JR | DB | 2 | 0 | 2 | 2 | 1.00 |
| 5 | Davonte Brown | UCF | JR | CB | 1 | 1 | 0 | 1 | 1.00 |
| 5 | Ja'Von Hicks | Cincinnati | SR | S | 1 | 1 | 0 | 1 | 1.00 |
| 5 | Armorion Smith | Cincinnati | FR | S | 1 | 1 | 0 | 1 | 1.00 |
| 5 | Joel Williams | Memphis | SO | DB | 1 | 1 | 0 | 1 | 1.00 |
| 5 | Shanon Reid | SMU | SR | LB | 1 | 1 | 0 | 1 | 1.00 |
| 5 | Divaad Wilson | UCF | SR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 5 | Jarvis Ware | UCF | SR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 5 | Arquon Bush | Cincinnati | SR | CB | 1 | 0 | 1 | 1 | 1.00 |
| 5 | Jalen Emery | Houston | FR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 5 | Abdul-Lateef Audu | Houston | JR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 5 | Art Green | Houston | SR | DB | 1 | 0 | 1 | 1 | 1.00 |
| 5 | AJ Davis | SMU | FR | CB | 1 | 0 | 1 | 1 | 1.00 |
| 5 | Matthew Peters | Navy | JR | CB | 1 | 0 | 1 | 1 | 1.00 |
| 5 | Donald Berniard Jr. | Navy | JR | NG | 1 | 0 | 1 | 1 | 1.00 |
| 5 | Tre'Mon Morris-Brash | UCF | SR | DE | 2 | 0 | 1 | 1 | 0.50 |
| 5 | Anthony Montalvo | UCF | SR | DT | 2 | 0 | 1 | 1 | 0.50 |
| 5 | Ja'Cari Henderson | UCF | FR | DB | 2 | 0 | 1 | 1 | 0.50 |
| 5 | Macon Clark | Tulane | SR | S | 2 | 0 | 1 | 1 | 0.50 |
| 5 | Keith Cooper Jr. | Tulane | SO | DL | 2 | 0 | 1 | 1 | 0.50 |
| 5 | Nick Anderson | Tulane | SR | LB | 2 | 0 | 1 | 1 | 0.50 |
| 5 | Dorian Williams | Tulane | SR | LB | 2 | 0 | 1 | 1 | 0.50 |
| 5 | Larry Brooks | Tulane | SR | S | 2 | 0 | 1 | 1 | 0.50 |