2022 American Athletic Conference Leaders Passes Defended - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Gervarrius Owens | Houston | SR | DB | 2 | 1 | 4 | 5 | 2.50 |
| 1 | Art Green | Houston | SR | DB | 2 | 1 | 1 | 2 | 1.00 |
| 1 | Aamaris Brown | S Florida | FR | DB | 2 | 1 | 1 | 2 | 1.00 |
| 1 | Jarius Monroe | Tulane | JR | DB | 2 | 1 | 1 | 2 | 1.00 |
| 1 | Taj Ward | Cincinnati | SR | CB | 3 | 1 | 1 | 2 | 0.67 |
| 1 | Jireh Wilson | ECU | JR | SAF | 1 | 1 | 0 | 1 | 1.00 |
| 1 | Quindell Johnson | Memphis | SR | DB | 1 | 1 | 0 | 1 | 1.00 |
| 1 | Jayce Rogers | Houston | SR | DB | 2 | 1 | 0 | 1 | 0.50 |
| 1 | Dwayne Boyles | S Florida | SR | LB | 2 | 1 | 0 | 1 | 0.50 |
| 1 | Ja'Von Hicks | Cincinnati | SR | S | 3 | 1 | 0 | 1 | 0.33 |
| 1 | Armorion Smith | Cincinnati | FR | S | 3 | 1 | 0 | 1 | 0.33 |
| 1 | Bryon Threats | Cincinnati | SO | S | 3 | 1 | 0 | 1 | 0.33 |