2022 American Athletic Conference Leaders Total Defense - Games vs. FBS Teams With Winning Record Only through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 6 | 1244 | 1223 | 447 | 2467 | 5.52 | 411.2 |
| 2 | Tulsa | 7 | 1363 | 1659 | 494 | 3022 | 6.12 | 431.7 |
| 3 | Houston | 6 | 843 | 1734 | 445 | 2577 | 5.79 | 429.5 |
| 4 | Memphis | 6 | 866 | 1812 | 457 | 2678 | 5.86 | 446.3 |
| 5 | Temple | 6 | 1159 | 1816 | 436 | 2975 | 6.82 | 495.8 |
| 6 | SMU | 8 | 1608 | 2037 | 533 | 3645 | 6.84 | 455.6 |
| 7 | Navy | 8 | 884 | 2233 | 463 | 3117 | 6.73 | 389.6 |
| 8 | UCF | 8 | 1256 | 2260 | 566 | 3516 | 6.21 | 439.5 |
| 9 | East Carolina | 8 | 903 | 2299 | 528 | 3202 | 6.06 | 400.3 |
| 10 | South Florida | 8 | 1884 | 2376 | 571 | 4260 | 7.46 | 532.5 |
| 11 | Tulane | 10 | 1643 | 2442 | 784 | 4085 | 5.21 | 408.5 |