2022 American Athletic Conference Leaders Passing Defense - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Tulsa | 1 | 19 | 11 | 57.9 | 125 | 6.6 | 2 | 1 | 137.37 | 19.0 | 125.0 |
| 2 | Cincinnati | 1 | 22 | 13 | 59.1 | 162 | 7.4 | 1 | 0 | 135.95 | 22.0 | 162.0 |
| 3 | UCF | 2 | 72 | 43 | 59.7 | 630 | 8.8 | 7 | 1 | 162.52 | 36.0 | 315.0 |
| 4 | Houston | 1 | 26 | 16 | 61.5 | 189 | 7.3 | 3 | 0 | 160.68 | 26.0 | 189.0 |
| 5 | South Florida | 1 | 36 | 23 | 63.9 | 329 | 9.1 | 2 | 0 | 158.99 | 36.0 | 329.0 |
| 6 | Tulane | 2 | 83 | 58 | 69.9 | 612 | 7.4 | 6 | 1 | 153.26 | 41.5 | 306.0 |
| 7 | SMU | 2 | 44 | 32 | 72.7 | 437 | 9.9 | 6 | 0 | 201.16 | 22.0 | 218.5 |
| 8 | Memphis | 2 | 78 | 58 | 74.4 | 608 | 7.8 | 6 | 1 | 162.66 | 39.0 | 304.0 |
| 9 | East Carolina | 1 | 35 | 28 | 80.0 | 350 | 10.0 | 2 | 0 | 182.86 | 35.0 | 350.0 |
| 10 | Navy | 1 | 21 | 17 | 81.0 | 269 | 12.8 | 4 | 1 | 241.89 | 21.0 | 269.0 |