2022 American Athletic Conference Leaders Opponent First Downs - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 1 | 15 | 5 | 2 | 22 | 22.0 |
| 2 | Tulsa | 1 | 18 | 6 | 0 | 24 | 24.0 |
| 3 | Navy | 1 | 6 | 8 | 1 | 15 | 15.0 |
| 4 | Houston | 1 | 4 | 9 | 1 | 14 | 14.0 |
| 5 | SMU | 2 | 24 | 15 | 2 | 41 | 20.5 |
| 5 | South Florida | 1 | 14 | 15 | 1 | 30 | 30.0 |
| 7 | East Carolina | 1 | 5 | 16 | 1 | 22 | 22.0 |
| 8 | UCF | 2 | 13 | 25 | 3 | 41 | 20.5 |
| 9 | Tulane | 2 | 14 | 29 | 1 | 44 | 22.0 |
| 10 | Memphis | 2 | 15 | 34 | 4 | 53 | 26.5 |