2022 American Athletic Conference Leaders Rushing Defense - Games vs. Unranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Navy | 11 | 321 | 1001 | 3.12 | 6 | 29.18 | 91.00 |
| 2 | East Carolina | 12 | 393 | 1421 | 3.62 | 14 | 32.75 | 118.42 |
| 3 | Memphis | 11 | 374 | 1304 | 3.49 | 12 | 34.00 | 118.55 |
| 4 | Cincinnati | 12 | 505 | 1771 | 3.51 | 16 | 42.08 | 147.58 |
| 5 | Houston | 12 | 421 | 1775 | 4.22 | 18 | 35.08 | 147.92 |
| 6 | UCF | 12 | 430 | 1803 | 4.19 | 21 | 35.83 | 150.25 |
| 7 | Tulane | 12 | 472 | 1814 | 3.84 | 14 | 39.33 | 151.17 |
| 8 | Temple | 12 | 506 | 2311 | 4.57 | 21 | 42.17 | 192.58 |
| 9 | Tulsa | 11 | 455 | 2138 | 4.70 | 19 | 41.36 | 194.36 |
| 10 | SMU | 11 | 458 | 2146 | 4.69 | 22 | 41.64 | 195.09 |
| 11 | South Florida | 11 | 409 | 2582 | 6.31 | 33 | 37.18 | 234.73 |