2022 American Athletic Conference Leaders Passes Defended - Games at Home Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Navy | 5 | 5 | 22 | 27 | 5.40 |
| 2 | Tulane | 8 | 10 | 33 | 43 | 5.38 |
| 3 | Memphis | 7 | 10 | 25 | 35 | 5.00 |
| 3 | UCF | 7 | 2 | 33 | 35 | 5.00 |
| 5 | East Carolina | 7 | 9 | 24 | 33 | 4.71 |
| 6 | Houston | 6 | 1 | 27 | 28 | 4.67 |
| 7 | Temple | 7 | 5 | 25 | 30 | 4.29 |
| 8 | Cincinnati | 6 | 3 | 20 | 23 | 3.83 |
| 9 | SMU | 6 | 6 | 14 | 20 | 3.33 |
| 10 | Tulsa | 6 | 4 | 14 | 18 | 3.00 |
| 11 | South Florida | 6 | 2 | 12 | 14 | 2.33 |