2022 American Athletic Conference Leaders First Downs - Games vs. Non-Conference Teams Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | SMU | 5 | 44 | 74 | 14 | 132 | 26.4 |
| 2 | Tulsa | 4 | 34 | 58 | 11 | 103 | 25.8 |
| 3 | UCF | 5 | 64 | 46 | 12 | 122 | 24.4 |
| 4 | East Carolina | 5 | 43 | 61 | 16 | 120 | 24.0 |
| 5 | Memphis | 5 | 55 | 50 | 6 | 111 | 22.2 |
| 5 | Tulane | 5 | 53 | 47 | 11 | 111 | 22.2 |
| 7 | Houston | 5 | 38 | 55 | 10 | 103 | 20.6 |
| 8 | Cincinnati | 5 | 31 | 62 | 6 | 99 | 19.8 |
| 9 | South Florida | 4 | 34 | 29 | 3 | 66 | 16.5 |
| 10 | Temple | 4 | 22 | 33 | 6 | 61 | 15.3 |
| 11 | Navy | 4 | 37 | 15 | 7 | 59 | 14.8 |