2022 American Athletic Conference Leaders First Downs - Games vs. FBS Teams With Winning Record Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | SMU | 8 | 76 | 114 | 25 | 215 | 26.9 |
| 2 | East Carolina | 8 | 63 | 87 | 20 | 170 | 21.3 |
| 2 | Tulsa | 7 | 52 | 72 | 20 | 144 | 20.6 |
| 4 | Memphis | 6 | 52 | 74 | 12 | 138 | 23.0 |
| 4 | Tulane | 10 | 93 | 93 | 12 | 198 | 19.8 |
| 4 | Navy | 8 | 106 | 29 | 12 | 147 | 18.4 |
| 7 | Temple | 6 | 15 | 88 | 11 | 114 | 19.0 |
| 7 | South Florida | 8 | 66 | 70 | 11 | 147 | 18.4 |
| 9 | UCF | 8 | 85 | 92 | 10 | 187 | 23.4 |
| 10 | Houston | 6 | 37 | 100 | 7 | 144 | 24.0 |
| 11 | Cincinnati | 6 | 36 | 61 | 4 | 101 | 16.8 |