2022 American Athletic Conference Leaders Sacks - Games vs. FBS Teams With Non-Winning Record Only through 01/09/2023
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Cincinnati | 6 | 23.0 | 158 | 3.83 |
| 2 | Temple | 5 | 15.0 | 75 | 3.00 |
| 3 | Navy | 3 | 8.0 | 44 | 2.67 |
| 4 | Tulane | 3 | 7.0 | 43 | 2.33 |
| 5 | SMU | 4 | 9.0 | 62 | 2.25 |
| 6 | Memphis | 6 | 13.0 | 70 | 2.17 |
| 7 | Houston | 7 | 12.0 | 71 | 1.71 |
| 8 | UCF | 5 | 8.0 | 54 | 1.60 |
| 9 | East Carolina | 4 | 6.0 | 33 | 1.50 |
| 10 | South Florida | 3 | 1.0 | 4 | 0.33 |
| 11 | Tulsa | 4 | 1.0 | 9 | 0.25 |