2022 American Athletic Conference Leaders Interceptions - Games vs. Unranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Memphis | 11 | 15 | 292 | 3 | 1.36 |
| 2 | Houston | 12 | 8 | 222 | 1 | 0.67 |
| 3 | East Carolina | 12 | 11 | 154 | 1 | 0.92 |
| 4 | Cincinnati | 12 | 11 | 149 | 2 | 0.92 |
| 5 | Temple | 12 | 6 | 136 | 2 | 0.50 |
| 6 | SMU | 11 | 10 | 113 | 0 | 0.91 |
| 7 | Navy | 11 | 7 | 57 | 0 | 0.64 |
| 8 | Tulane | 12 | 11 | 53 | 0 | 0.92 |
| 9 | South Florida | 11 | 6 | 49 | 0 | 0.55 |
| 10 | UCF | 12 | 5 | 12 | 0 | 0.42 |
| 11 | Tulsa | 11 | 5 | 5 | 0 | 0.45 |