2022 American Athletic Conference Leaders Sacks - Games vs. Unranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Temple | 12 | 38.0 | 214 | 3.17 |
| 2 | Cincinnati | 12 | 34.0 | 235 | 2.83 |
| 3 | Houston | 12 | 28.0 | 161 | 2.33 |
| 3 | Navy | 11 | 28.0 | 150 | 2.55 |
| 5 | Tulane | 12 | 24.0 | 152 | 2.00 |
| 6 | East Carolina | 12 | 23.0 | 172 | 1.92 |
| 7 | SMU | 11 | 21.0 | 142 | 1.91 |
| 8 | UCF | 12 | 19.0 | 133 | 1.58 |
| 8 | Memphis | 11 | 19.0 | 113 | 1.73 |
| 10 | Tulsa | 11 | 14.0 | 102 | 1.27 |
| 11 | South Florida | 11 | 10.0 | 54 | 0.91 |