2022 American Athletic Conference Leaders Sacks - Games in August/September Only through 01/09/2023
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Houston | 5 | 14.0 | 91 | 2.80 |
| 2 | Temple | 4 | 15.0 | 90 | 3.75 |
| 3 | Cincinnati | 4 | 12.0 | 87 | 3.00 |
| 4 | SMU | 4 | 11.0 | 74 | 2.75 |
| 5 | East Carolina | 4 | 8.0 | 60 | 2.00 |
| 6 | UCF | 4 | 10.0 | 58 | 2.50 |
| 7 | Navy | 3 | 10.0 | 50 | 3.33 |
| 8 | Tulane | 5 | 6.0 | 37 | 1.20 |
| 9 | Memphis | 4 | 6.0 | 32 | 1.50 |
| 10 | South Florida | 4 | 6.0 | 27 | 1.50 |
| 11 | Tulsa | 4 | 4.0 | 18 | 1.00 |