2022 American Athletic Conference Leaders First Downs - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Houston | 11 | 78 | 171 | 15 | 264 | 24.0 |
| 2 | Memphis | 11 | 94 | 139 | 19 | 252 | 22.9 |
| 3 | SMU | 10 | 102 | 126 | 23 | 251 | 25.1 |
| 4 | UCF | 10 | 112 | 124 | 12 | 248 | 24.8 |
| 4 | East Carolina | 11 | 86 | 138 | 24 | 248 | 22.5 |
| 6 | Tulane | 11 | 116 | 107 | 15 | 238 | 21.6 |
| 7 | Tulsa | 10 | 70 | 107 | 25 | 202 | 20.2 |
| 8 | Navy | 11 | 148 | 31 | 15 | 194 | 17.6 |
| 9 | South Florida | 9 | 85 | 82 | 13 | 180 | 20.0 |
| 10 | Temple | 9 | 29 | 133 | 16 | 178 | 19.8 |
| 11 | Cincinnati | 9 | 62 | 99 | 7 | 168 | 18.7 |