2022 American Athletic Conference Leaders Tackles For Loss - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2023
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Houston | 11 | 74.0 | 259 | 6.73 |
| 2 | East Carolina | 11 | 66.0 | 261 | 6.00 |
| 3 | Navy | 11 | 65.0 | 263 | 5.91 |
| 4 | Temple | 9 | 60.0 | 238 | 6.67 |
| 5 | Cincinnati | 9 | 59.0 | 226 | 6.56 |
| 6 | Memphis | 11 | 56.0 | 183 | 5.09 |
| 7 | UCF | 10 | 50.0 | 199 | 5.00 |
| 8 | Tulane | 11 | 48.0 | 178 | 4.36 |
| 8 | Tulsa | 10 | 48.0 | 168 | 4.80 |
| 10 | SMU | 10 | 45.0 | 206 | 4.50 |
| 11 | South Florida | 9 | 42.0 | 122 | 4.67 |