2022 Mid-American Conference Leaders Long All Purpose Plays - Games in October Only through 01/09/2023
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Corey Crooms | W Mich | JR | WR | 4 | 2 | 2 | 2 | 2 | 2 | 0 | 0 |
| 1 | Sam Wiglusz | Ohio | SR | WR | 4 | 3 | 2 | 2 | 2 | 2 | 0 | 0 |
| 3 | Alex Adams | Akron | SO | WR | 5 | 5 | 2 | 1 | 1 | 1 | 1 | 0 |
| 3 | Al-Jay Henderson | Buffalo | FR | RB | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 3 | Jaylon Jackson | EMU | JR | RB | 5 | 3 | 2 | 1 | 1 | 1 | 1 | 0 |
| 3 | Shocky Jacques-Louis | Akron | SR | WR | 5 | 5 | 1 | 1 | 1 | 1 | 1 | 0 |
| 3 | Miles Marshall | Miami (Oh) | JR | WR | 5 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Jahmin Muse | Buffalo | SR | S | 4 | 2 | 2 | 2 | 1 | 1 | 0 | 0 |
| 3 | Andreas Paaske | EMU | SO | TE | 5 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | James Patterson | Buffalo | SR | LB | 4 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Aveon Smith | Miami (Oh) | FR | QB | 3 | 2 | 1 | 1 | 1 | 1 | 0 | 0 |
| 3 | Sean Tyler | W Mich | JR | RB | 4 | 3 | 2 | 1 | 1 | 1 | 0 | 0 |
| 3 | Delano Ware | W Mich | SR | S | 4 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Mike Washington | Buffalo | FR | RB | 4 | 2 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 | Harrison Waylee | N Illinois | SO | RB | 4 | 3 | 3 | 3 | 2 | 1 | 0 | 0 |