2022 Mid-American Conference Leaders Rushing Defense - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Eastern Michigan | 1 | 23 | 170 | 7.39 | 2 | 23.00 | 170.00 |
| 2 | Buffalo | 1 | 26 | 149 | 5.73 | 4 | 26.00 | 149.00 |
| 3 | Bowling Green | 2 | 56 | 314 | 5.61 | 3 | 28.00 | 157.00 |
| 4 | Miami (Ohio) | 2 | 57 | 157 | 2.75 | 2 | 28.50 | 78.50 |
| 5 | Central Michigan | 2 | 64 | 291 | 4.55 | 6 | 32.00 | 145.50 |
| 6 | Ohio | 2 | 66 | 397 | 6.02 | 5 | 33.00 | 198.50 |
| 7 | Northern Illinois | 2 | 74 | 276 | 3.73 | 1 | 37.00 | 138.00 |
| 7 | Kent State | 3 | 111 | 523 | 4.71 | 7 | 37.00 | 174.33 |
| 9 | Western Michigan | 2 | 84 | 435 | 5.18 | 3 | 42.00 | 217.50 |
| 10 | Toledo | 1 | 44 | 281 | 6.39 | 5 | 44.00 | 281.00 |
| 11 | Akron | 2 | 93 | 498 | 5.35 | 11 | 46.50 | 249.00 |
| 12 | Ball State | 1 | 51 | 218 | 4.27 | 5 | 51.00 | 218.00 |