2022 Mid-American Conference Leaders Total Defense - Games vs. FBS non-Power 5 Conference Teams Only through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Toledo | 12 | 1679 | 2012 | 814 | 3691 | 4.53 | 307.6 |
| 2 | Ball State | 10 | 1893 | 2174 | 808 | 4067 | 5.03 | 406.7 |
| 3 | Central Michigan | 9 | 1519 | 1851 | 654 | 3370 | 5.15 | 374.4 |
| 4 | Western Michigan | 9 | 1204 | 1972 | 585 | 3176 | 5.43 | 352.9 |
| 5 | Eastern Michigan | 11 | 1718 | 2339 | 738 | 4057 | 5.50 | 368.8 |
| 6 | Kent State | 8 | 1286 | 2115 | 616 | 3401 | 5.52 | 425.1 |
| 7 | Akron | 9 | 1262 | 1987 | 588 | 3249 | 5.53 | 361.0 |
| 7 | Miami (Ohio) | 10 | 1570 | 2344 | 708 | 3914 | 5.53 | 391.4 |
| 9 | Bowling Green | 10 | 1764 | 2158 | 697 | 3922 | 5.63 | 392.2 |
| 10 | Northern Illinois | 9 | 1273 | 2200 | 614 | 3473 | 5.66 | 385.9 |
| 11 | Ohio | 11 | 1439 | 2863 | 753 | 4302 | 5.71 | 391.1 |
| 12 | Buffalo | 11 | 1825 | 2414 | 719 | 4239 | 5.90 | 385.4 |