2016 Atlantic Coast Conference Leaders Rushing Defense - Games vs. Non-Conference Teams Only through 01/09/2017
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Boston College | 5 | 125 | 170 | 1.36 | 3 | 25.00 | 34.00 |
| 2 | Miami (Florida) | 5 | 193 | 456 | 2.36 | 4 | 38.60 | 91.20 |
| 3 | Wake Forest | 5 | 188 | 535 | 2.85 | 5 | 37.60 | 107.00 |
| 4 | North Carolina State | 5 | 166 | 542 | 3.27 | 7 | 33.20 | 108.40 |
| 5 | Duke | 4 | 153 | 442 | 2.89 | 4 | 38.25 | 110.50 |
| 6 | Pittsburgh | 5 | 176 | 579 | 3.29 | 13 | 35.20 | 115.80 |
| 7 | Clemson | 6 | 192 | 696 | 3.63 | 5 | 32.00 | 116.00 |
| 8 | Virginia Tech | 5 | 186 | 646 | 3.47 | 7 | 37.20 | 129.20 |
| 9 | Florida State | 5 | 170 | 656 | 3.86 | 6 | 34.00 | 131.20 |
| 10 | Louisville | 5 | 191 | 666 | 3.49 | 5 | 38.20 | 133.20 |
| 11 | Georgia Tech | 5 | 186 | 749 | 4.03 | 5 | 37.20 | 149.80 |
| 12 | Syracuse | 4 | 149 | 606 | 4.07 | 8 | 37.25 | 151.50 |
| 13 | Virginia | 4 | 160 | 704 | 4.40 | 7 | 40.00 | 176.00 |
| 14 | North Carolina | 5 | 253 | 1153 | 4.56 | 8 | 50.60 | 230.60 |