2016 Atlantic Coast Conference Leaders Rushing Defense - Games vs. FBS Power 5 Conference Teams Only through 01/09/2017
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Florida State | 11 | 377 | 1222 | 3.24 | 15 | 34.27 | 111.09 |
| 2 | North Carolina State | 9 | 293 | 1026 | 3.50 | 13 | 32.56 | 114.00 |
| 3 | Louisville | 10 | 376 | 1237 | 3.29 | 5 | 37.60 | 123.70 |
| 4 | Pittsburgh | 11 | 373 | 1398 | 3.75 | 26 | 33.91 | 127.09 |
| 5 | Clemson | 13 | 460 | 1755 | 3.82 | 19 | 35.38 | 135.00 |
| 6 | Virginia Tech | 11 | 418 | 1596 | 3.82 | 19 | 38.00 | 145.09 |
| 7 | Miami (Florida) | 9 | 345 | 1350 | 3.91 | 8 | 38.33 | 150.00 |
| 8 | Boston College | 9 | 331 | 1369 | 4.14 | 14 | 36.78 | 152.11 |
| 9 | Wake Forest | 9 | 329 | 1431 | 4.35 | 16 | 36.56 | 159.00 |
| 10 | Georgia Tech | 11 | 395 | 1987 | 5.03 | 22 | 35.91 | 180.64 |
| 11 | Duke | 9 | 360 | 1743 | 4.84 | 15 | 40.00 | 193.67 |
| 12 | Virginia | 9 | 370 | 1877 | 5.07 | 16 | 41.11 | 208.56 |
| 13 | North Carolina | 11 | 537 | 2402 | 4.47 | 24 | 48.82 | 218.36 |
| 14 | Syracuse | 8 | 348 | 2094 | 6.02 | 27 | 43.50 | 261.75 |