2016 Atlantic Coast Conference Leaders Opponent First Downs - Games vs. FBS Teams With Non-Winning Record Only through 01/09/2017
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Duke | 2 | 13 | 27 | 0 | 40 | 20.0 |
| 2 | Syracuse | 2 | 16 | 30 | 2 | 48 | 24.0 |
| 3 | Clemson | 2 | 10 | 15 | 4 | 29 | 14.5 |
| 3 | North Carolina State | 4 | 25 | 32 | 4 | 61 | 15.3 |
| 5 | North Carolina | 3 | 26 | 30 | 5 | 61 | 20.3 |
| 5 | Georgia Tech | 4 | 37 | 48 | 5 | 90 | 22.5 |
| 7 | Florida State | 2 | 7 | 21 | 6 | 34 | 17.0 |
| 7 | Miami (Florida) | 4 | 20 | 43 | 6 | 69 | 17.3 |
| 7 | Wake Forest | 5 | 31 | 58 | 6 | 95 | 19.0 |
| 10 | Boston College | 5 | 15 | 38 | 8 | 61 | 12.2 |
| 10 | Virginia Tech | 5 | 48 | 52 | 8 | 108 | 21.6 |
| 12 | Pittsburgh | 4 | 31 | 53 | 9 | 93 | 23.3 |
| 13 | Louisville | 5 | 34 | 37 | 11 | 82 | 16.4 |
| 14 | Virginia | 4 | 24 | 54 | 12 | 90 | 22.5 |