2016 Atlantic Coast Conference Leaders Total Defense - Games in December/January Only through 01/09/2017
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Miami (Florida) | 1 | 95 | 134 | 65 | 229 | 3.52 | 229.0 |
| 2 | Florida State | 1 | 89 | 163 | 74 | 252 | 3.41 | 252.0 |
| 3 | North Carolina | 1 | 129 | 154 | 61 | 283 | 4.64 | 283.0 |
| 4 | North Carolina State | 1 | 156 | 158 | 81 | 314 | 3.88 | 314.0 |
| 5 | Georgia Tech | 1 | 149 | 175 | 70 | 324 | 4.63 | 324.0 |
| 6 | Boston College | 1 | 128 | 229 | 69 | 357 | 5.17 | 357.0 |
| 7 | Wake Forest | 1 | -20 | 396 | 72 | 376 | 5.22 | 376.0 |
| 8 | Louisville | 1 | 177 | 217 | 70 | 394 | 5.63 | 394.0 |
| 9 | Pittsburgh | 1 | 248 | 214 | 86 | 462 | 5.37 | 462.0 |
| 10 | Virginia Tech | 2 | 218 | 566 | 140 | 784 | 5.60 | 392.0 |
| 11 | Clemson | 3 | 411 | 566 | 193 | 977 | 5.06 | 325.7 |