2016 Atlantic Coast Conference Leaders Interceptions - Games vs. Ranked Teams Only (AP Poll) through 01/09/2017
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Clemson | 7 | 8 | 107 | 0 | 1.14 |
| 2 | Florida State | 5 | 6 | 15 | 0 | 1.20 |
| 3 | Louisville | 3 | 5 | 37 | 0 | 1.67 |
| 4 | Pittsburgh | 4 | 4 | 70 | 0 | 1.00 |
| 4 | Syracuse | 6 | 4 | 51 | 0 | 0.67 |
| 6 | Georgia Tech | 3 | 3 | 3 | 0 | 1.00 |
| 7 | Virginia Tech | 2 | 2 | 1 | 0 | 1.00 |
| 7 | Boston College | 4 | 2 | 41 | 0 | 0.50 |
| 7 | Miami (Florida) | 4 | 2 | 11 | 0 | 0.50 |
| 7 | Wake Forest | 4 | 2 | 1 | 0 | 0.50 |
| 11 | Duke | 3 | 1 | 36 | 1 | 0.33 |
| 11 | Virginia | 3 | 1 | 30 | 0 | 0.33 |
| 11 | North Carolina State | 3 | 1 | 28 | 1 | 0.33 |