2022 Atlantic Coast Conference Leaders Interceptions - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Syracuse | 4 | 5 | 34 | 0 | 1.25 |
| 2 | Pittsburgh | 2 | 4 | 13 | 0 | 2.00 |
| 2 | Louisville | 3 | 4 | 48 | 0 | 1.33 |
| 4 | Miami (Florida) | 3 | 3 | 4 | 0 | 1.00 |
| 5 | Duke | 1 | 2 | 33 | 0 | 2.00 |
| 5 | North Carolina State | 2 | 2 | 5 | 0 | 1.00 |
| 5 | Clemson | 4 | 2 | 35 | 1 | 0.50 |
| 8 | Virginia Tech | 1 | 1 | 0 | 0 | 1.00 |
| 8 | Boston College | 3 | 1 | 0 | 0 | 0.33 |
| 8 | North Carolina | 4 | 1 | 40 | 0 | 0.25 |
| 8 | Georgia Tech | 4 | 1 | 0 | 0 | 0.25 |