2016 Atlantic Coast Conference Leaders First Downs - Games in August/September Only through 01/09/2017
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Florida State | 4 | 57 | 42 | 10 | 109 | 27.3 |
| 2 | Louisville | 4 | 55 | 58 | 12 | 125 | 31.3 |
| 3 | Georgia Tech | 4 | 48 | 13 | 8 | 69 | 17.3 |
| 4 | Wake Forest | 4 | 43 | 27 | 3 | 73 | 18.3 |
| 5 | Pittsburgh | 4 | 41 | 34 | 3 | 78 | 19.5 |
| 6 | Duke | 4 | 40 | 51 | 6 | 97 | 24.3 |
| 7 | Clemson | 4 | 34 | 52 | 8 | 94 | 23.5 |
| 8 | Virginia | 4 | 33 | 48 | 12 | 93 | 23.3 |
| 8 | Virginia Tech | 4 | 33 | 47 | 8 | 88 | 22.0 |
| 10 | North Carolina State | 3 | 30 | 41 | 4 | 75 | 25.0 |
| 11 | Miami (Florida) | 3 | 29 | 31 | 1 | 61 | 20.3 |
| 11 | Boston College | 4 | 29 | 27 | 2 | 58 | 14.5 |
| 13 | Syracuse | 4 | 28 | 62 | 8 | 98 | 24.5 |
| 14 | North Carolina | 4 | 24 | 58 | 7 | 89 | 22.3 |