2018 Conference USA Leaders Passes Defended - Games in August/September Only through 01/07/2019
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Western Kentucky | 5 | 5 | 27 | 32 | 6.40 |
| 2 | North Texas | 5 | 10 | 21 | 31 | 6.20 |
| 3 | Old Dominion | 5 | 4 | 24 | 28 | 5.60 |
| 4 | Marshall | 4 | 4 | 22 | 26 | 6.50 |
| 5 | Florida International | 5 | 5 | 15 | 20 | 4.00 |
| 6 | Charlotte | 5 | 3 | 15 | 18 | 3.60 |
| 6 | Rice | 5 | 2 | 16 | 18 | 3.60 |
| 8 | Southern Mississippi | 4 | 5 | 9 | 14 | 3.50 |
| 8 | UTEP | 5 | 1 | 13 | 14 | 2.80 |
| 10 | Middle Tennessee | 4 | 3 | 10 | 13 | 3.25 |
| 11 | Louisiana Tech | 4 | 2 | 10 | 12 | 3.00 |
| 11 | Florida Atlantic | 5 | 3 | 9 | 12 | 2.40 |
| 13 | UTSA | 5 | 3 | 8 | 11 | 2.20 |
| 14 | UAB | 4 | 4 | 6 | 10 | 2.50 |