2022 Conference USA Leaders Passes Defended - Games in August/September Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Middle Tennessee | 5 | 9 | 20 | 29 | 5.80 |
| 2 | UAB | 3 | 6 | 18 | 24 | 8.00 |
| 3 | Western Kentucky | 4 | 8 | 15 | 23 | 5.75 |
| 4 | UTEP | 5 | 2 | 20 | 22 | 4.40 |
| 5 | UTSA | 5 | 2 | 18 | 20 | 4.00 |
| 6 | Louisiana Tech | 4 | 3 | 14 | 17 | 4.25 |
| 7 | Rice | 4 | 4 | 11 | 15 | 3.75 |
| 8 | Florida Atlantic | 5 | 3 | 9 | 12 | 2.40 |
| 9 | Florida International | 3 | 2 | 9 | 11 | 3.67 |
| 9 | North Texas | 5 | 1 | 10 | 11 | 2.20 |
| 11 | Charlotte | 5 | 3 | 3 | 6 | 1.20 |