2018 American Athletic Conference Leaders Passes Defended - Games in August/September Only through 01/07/2019
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Houston | 4 | 3 | 26 | 29 | 7.25 |
| 2 | UCF | 4 | 8 | 24 | 32 | 8.00 |
| 2 | Tulane | 5 | 6 | 24 | 30 | 6.00 |
| 4 | Cincinnati | 5 | 4 | 21 | 25 | 5.00 |
| 5 | Temple | 5 | 7 | 20 | 27 | 5.40 |
| 5 | East Carolina | 4 | 1 | 20 | 21 | 5.25 |
| 7 | SMU | 5 | 3 | 17 | 20 | 4.00 |
| 8 | South Florida | 4 | 5 | 15 | 20 | 5.00 |
| 9 | Navy | 4 | 4 | 14 | 18 | 4.50 |
| 9 | Tulsa | 4 | 2 | 14 | 16 | 4.00 |
| 11 | Connecticut | 5 | 1 | 10 | 11 | 2.20 |
| 12 | Memphis | 5 | 3 | 9 | 12 | 2.40 |