2019 American Athletic Conference Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 01/13/2020
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Navy | 1 | 46 | 124 | 41 | 170 | 4.15 | 170.0 |
| 2 | Cincinnati | 3 | 409 | 481 | 182 | 890 | 4.89 | 296.7 |
| 3 | South Florida | 2 | 415 | 277 | 139 | 692 | 4.98 | 346.0 |
| 4 | Memphis | 2 | 476 | 226 | 125 | 702 | 5.62 | 351.0 |
| 5 | Tulane | 1 | 172 | 207 | 82 | 379 | 4.62 | 379.0 |
| 6 | Temple | 3 | 530 | 649 | 230 | 1179 | 5.13 | 393.0 |
| 7 | Connecticut | 2 | 308 | 479 | 138 | 787 | 5.70 | 393.5 |
| 8 | UCF | 2 | 312 | 476 | 160 | 788 | 4.93 | 394.0 |
| 9 | Tulsa | 2 | 445 | 364 | 146 | 809 | 5.54 | 404.5 |
| 10 | SMU | 1 | 236 | 188 | 78 | 424 | 5.44 | 424.0 |
| 11 | East Carolina | 1 | 191 | 314 | 70 | 505 | 7.21 | 505.0 |
| 12 | Houston | 2 | 403 | 772 | 128 | 1175 | 9.18 | 587.5 |