2021 Conference USA Leaders Passes Defended - Games in October Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | R'Tarriun Johnson | ODU | JR | S | 4 | 2 | 3 | 5 | 1.25 |
| 1 | Quincy Riley | MTSU | FR | CB | 2 | 2 | 2 | 4 | 2.00 |
| 1 | Gregory Grate | MTSU | JR | S | 4 | 2 | 2 | 4 | 1.00 |
| 1 | Steven Gilmore | Marshall | JR | DB | 4 | 2 | 1 | 3 | 0.75 |
| 1 | Cory McCoy | Marshall | SR | S | 4 | 2 | 1 | 3 | 0.75 |
| 1 | Naeem Smith | Rice | SR | S | 4 | 2 | 1 | 3 | 0.75 |
| 1 | DQ Thomas | MTSU | SR | LB | 4 | 2 | 0 | 2 | 0.50 |
| 8 | Roger Cray | ODU | SR | CB | 3 | 1 | 6 | 7 | 2.33 |
| 8 | Zyon Gilbert | FAU | SR | CB | 4 | 1 | 6 | 7 | 1.75 |
| 8 | Will Ignont | Western Ky | JR | LB | 5 | 1 | 4 | 5 | 1.00 |
| 8 | Korel Smith | FAU | SR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 8 | Romain Mungin | FAU | SO | CB | 4 | 1 | 3 | 4 | 1.00 |
| 8 | Nazeeh Johnson | Marshall | SR | S | 4 | 1 | 3 | 4 | 1.00 |
| 8 | Miles McCord | Rice | JR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 8 | Antwon Kincade | Western Ky | SR | DB | 5 | 1 | 3 | 4 | 0.80 |
| 8 | Jordan Helm | FAU | SR | S | 4 | 1 | 2 | 3 | 0.75 |
| 8 | Dy'vonne Inyang | UTEP | SR | DB | 4 | 1 | 2 | 3 | 0.75 |
| 8 | Clarence Hicks | UTSA | SR | OLB | 4 | 1 | 2 | 3 | 0.75 |
| 8 | Corey Mayfield Jr. | UTSA | SR | CB | 4 | 1 | 2 | 3 | 0.75 |
| 8 | A.J. Brathwaite, Jr. | Western Ky | SO | DB | 4 | 1 | 2 | 3 | 0.75 |
| 8 | George Nyakwol | Rice | SR | DB | 1 | 1 | 1 | 2 | 2.00 |
| 8 | Grayson Cash | UAB | JR | S | 4 | 1 | 1 | 2 | 0.50 |
| 8 | Kyle Harrell | UAB | SR | OLB | 4 | 1 | 1 | 2 | 0.50 |
| 8 | Ahman Ross | FAU | JR | S | 4 | 1 | 1 | 2 | 0.50 |
| 8 | Deidrick Stanley II | MTSU | FR | S | 4 | 1 | 1 | 2 | 0.50 |
| 8 | Eric Scott, Jr. | USM | JR | DB | 4 | 1 | 1 | 2 | 0.50 |
| 8 | Malik Shorts | USM | SO | DB | 4 | 1 | 1 | 2 | 0.50 |
| 8 | Dennis Barnes | UTEP | JR | DB | 4 | 1 | 1 | 2 | 0.50 |
| 8 | Torey Richardson | UTEP | SO | CB | 4 | 1 | 1 | 2 | 0.50 |
| 8 | Jahmal Sam | UTSA | SO | S | 4 | 1 | 1 | 2 | 0.50 |
| 8 | Kody Fulp | La Tech | JR | LB | 3 | 1 | 0 | 1 | 0.33 |
| 8 | Jon Alexander | Charlotte | SR | DB | 3 | 1 | 0 | 1 | 0.33 |
| 8 | Jarrett Preston | UTSA | JR | S | 3 | 1 | 0 | 1 | 0.33 |
| 8 | Noah Wilder | UAB | SR | LB | 4 | 1 | 0 | 1 | 0.25 |
| 8 | Starling Thomas V | UAB | JR | CB | 4 | 1 | 0 | 1 | 0.25 |
| 8 | Jaiden Cole | La Tech | JR | DB | 4 | 1 | 0 | 1 | 0.25 |
| 8 | Eli Neal | Marshall | SO | LB | 4 | 1 | 0 | 1 | 0.25 |
| 8 | Jalen Jackson | MTSU | FR | CB | 4 | 1 | 0 | 1 | 0.25 |
| 8 | Decorian Patterson | MTSU | SO | CB | 4 | 1 | 0 | 1 | 0.25 |
| 8 | Marley Cook | MTSU | FR | DT | 4 | 1 | 0 | 1 | 0.25 |
| 8 | Justin Whisenhunt | Charlotte | SR | LB | 4 | 1 | 0 | 1 | 0.25 |
| 8 | Marcus Robitaille | Charlotte | SO | DB | 4 | 1 | 0 | 1 | 0.25 |
| 8 | Harold West | N Texas | FR | DB | 4 | 1 | 0 | 1 | 0.25 |
| 8 | Kirk Lockhart | Rice | SO | S | 4 | 1 | 0 | 1 | 0.25 |
| 8 | Tyrice Knight | UTEP | JR | LB | 4 | 1 | 0 | 1 | 0.25 |
| 8 | Tyson Wilson | UTEP | SO | DB | 4 | 1 | 0 | 1 | 0.25 |
| 8 | Tariq Woolen | UTSA | SR | CB | 4 | 1 | 0 | 1 | 0.25 |
| 8 | Trevor Harmanson | UTSA | SR | ILB | 4 | 1 | 0 | 1 | 0.25 |
| 8 | Dadrian Taylor | UTSA | SR | OLB | 4 | 1 | 0 | 1 | 0.25 |
| 8 | Demetrius Cain | Western Ky | SR | LB | 5 | 1 | 0 | 1 | 0.20 |