2021 Conference USA Leaders Passes Defended - Games in December/January Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Jahmal Sam | UTSA | SO | S | 1 | 1 | 1 | 2 | 2.00 |
| 1 | Zaylin Wood | MTSU | FR | DT | 1 | 1 | 0 | 1 | 1.00 |
| 1 | Antonio Parks | UTSA | SR | S | 2 | 1 | 0 | 1 | 0.50 |
| 1 | Michael Pitts | Western Ky | SR | DE | 2 | 1 | 0 | 1 | 0.50 |
| 1 | Miguel Edwards | Western Ky | SO | DB | 2 | 1 | 0 | 1 | 0.50 |