2021 Conference USA Leaders Opponent Penalties - Games at Home Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Old Dominion | 6 | 50 | 439 | 8.3 | 73.2 |
| 2 | Louisiana Tech | 6 | 42 | 423 | 7.0 | 70.5 |
| 3 | North Texas | 6 | 46 | 419 | 7.7 | 69.8 |
| 4 | Rice | 6 | 39 | 415 | 6.5 | 69.2 |
| 5 | Florida Atlantic | 6 | 46 | 413 | 7.7 | 68.8 |
| 5 | UTSA | 7 | 57 | 413 | 8.1 | 59.0 |
| 7 | Western Kentucky | 6 | 47 | 407 | 7.8 | 67.8 |
| 8 | Charlotte | 6 | 46 | 404 | 7.7 | 67.3 |
| 9 | UTEP | 6 | 44 | 395 | 7.3 | 65.8 |
| 10 | Southern Mississippi | 6 | 44 | 393 | 7.3 | 65.5 |
| 11 | Marshall | 6 | 38 | 338 | 6.3 | 56.3 |
| 12 | Florida International | 6 | 34 | 312 | 5.7 | 52.0 |
| 13 | UAB | 5 | 31 | 277 | 6.2 | 55.4 |
| 14 | Middle Tennessee | 5 | 30 | 241 | 6.0 | 48.2 |