2021 Conference USA Leaders Opponent Penalties - Games vs. FBS Teams With Winning Record Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Rice | 6 | 49 | 497 | 8.2 | 82.8 |
| 2 | Louisiana Tech | 6 | 46 | 476 | 7.7 | 79.3 |
| 3 | UTSA | 6 | 53 | 472 | 8.8 | 78.7 |
| 4 | North Texas | 7 | 50 | 461 | 7.1 | 65.9 |
| 5 | Florida Atlantic | 6 | 51 | 446 | 8.5 | 74.3 |
| 6 | Old Dominion | 7 | 45 | 418 | 6.4 | 59.7 |
| 7 | Southern Mississippi | 5 | 34 | 331 | 6.8 | 66.2 |
| 7 | Western Kentucky | 7 | 39 | 331 | 5.6 | 47.3 |
| 9 | Middle Tennessee | 5 | 38 | 322 | 7.6 | 64.4 |
| 10 | Marshall | 6 | 33 | 313 | 5.5 | 52.2 |
| 11 | UTEP | 4 | 26 | 296 | 6.5 | 74.0 |
| 12 | Florida International | 5 | 31 | 293 | 6.2 | 58.6 |
| 13 | Charlotte | 4 | 30 | 256 | 7.5 | 64.0 |
| 14 | UAB | 6 | 30 | 230 | 5.0 | 38.3 |