2021 Conference USA Leaders Passing Defense - Games vs. FBS Teams With Winning Record Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Southern Mississippi | 5 | 114 | 72 | 63.2 | 1057 | 9.3 | 9 | 5 | 158.32 | 22.8 | 211.4 |
| 2 | UTEP | 4 | 121 | 80 | 66.1 | 1020 | 8.4 | 7 | 1 | 154.37 | 30.3 | 255.0 |
| 3 | Charlotte | 4 | 125 | 88 | 70.4 | 1178 | 9.4 | 13 | 3 | 179.08 | 31.3 | 294.5 |
| 4 | UAB | 6 | 175 | 112 | 64.0 | 1661 | 9.5 | 14 | 3 | 166.69 | 29.2 | 276.8 |
| 5 | Rice | 6 | 192 | 126 | 65.6 | 1699 | 8.8 | 13 | 5 | 157.09 | 32.0 | 283.2 |
| 5 | Florida International | 5 | 192 | 141 | 73.4 | 1549 | 8.1 | 13 | 1 | 162.51 | 38.4 | 309.8 |
| 7 | Louisiana Tech | 6 | 201 | 140 | 69.7 | 1674 | 8.3 | 12 | 3 | 156.32 | 33.5 | 279.0 |
| 8 | North Texas | 7 | 202 | 120 | 59.4 | 1837 | 9.1 | 17 | 4 | 159.61 | 28.9 | 262.4 |
| 9 | Florida Atlantic | 6 | 205 | 130 | 63.4 | 1609 | 7.8 | 12 | 5 | 143.79 | 34.2 | 268.2 |
| 10 | Marshall | 6 | 209 | 125 | 59.8 | 1639 | 7.8 | 11 | 2 | 141.14 | 34.8 | 273.2 |
| 11 | Middle Tennessee | 5 | 211 | 121 | 57.3 | 1313 | 6.2 | 11 | 8 | 119.24 | 42.2 | 262.6 |
| 12 | Western Kentucky | 7 | 225 | 148 | 65.8 | 1811 | 8.0 | 19 | 10 | 152.37 | 32.1 | 258.7 |
| 13 | UTSA | 6 | 238 | 140 | 58.8 | 2125 | 8.9 | 19 | 5 | 155.96 | 39.7 | 354.2 |
| 14 | Old Dominion | 7 | 263 | 173 | 65.8 | 1915 | 7.3 | 19 | 4 | 147.74 | 37.6 | 273.6 |