2021 Conference USA Leaders Sacks Allowed - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Western Kentucky | 13 | 14.0 | 102 | 1.08 |
| 2 | North Texas | 13 | 15.0 | 96 | 1.15 |
| 3 | Marshall | 12 | 17.0 | 101 | 1.42 |
| 4 | UTSA | 13 | 19.0 | 116 | 1.46 |
| 4 | UTEP | 13 | 19.0 | 160 | 1.46 |
| 6 | Rice | 10 | 22.0 | 139 | 2.20 |
| 7 | Charlotte | 12 | 25.0 | 156 | 2.08 |
| 7 | Louisiana Tech | 11 | 25.0 | 165 | 2.27 |
| 9 | Middle Tennessee | 13 | 28.0 | 226 | 2.15 |
| 10 | Old Dominion | 12 | 29.0 | 185 | 2.42 |
| 10 | UAB | 11 | 29.0 | 207 | 2.64 |
| 12 | Florida Atlantic | 12 | 35.0 | 216 | 2.92 |
| 13 | Florida International | 12 | 41.0 | 283 | 3.42 |
| 14 | Southern Mississippi | 11 | 42.0 | 349 | 3.82 |