2021 Conference USA Leaders Sacks Allowed - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | North Texas | 11 | 12.0 | 78 | 1.09 |
| 2 | Western Kentucky | 11 | 13.0 | 93 | 1.18 |
| 3 | UTEP | 12 | 17.0 | 154 | 1.42 |
| 4 | Marshall | 12 | 19.0 | 115 | 1.58 |
| 4 | UTSA | 12 | 19.0 | 120 | 1.58 |
| 6 | Charlotte | 9 | 20.0 | 125 | 2.22 |
| 7 | Rice | 9 | 22.0 | 158 | 2.44 |
| 8 | Louisiana Tech | 9 | 23.0 | 151 | 2.56 |
| 8 | Middle Tennessee | 11 | 23.0 | 183 | 2.09 |
| 10 | Florida Atlantic | 10 | 29.0 | 180 | 2.90 |
| 10 | Old Dominion | 11 | 29.0 | 185 | 2.64 |
| 12 | UAB | 11 | 31.0 | 215 | 2.82 |
| 13 | Florida International | 10 | 39.0 | 267 | 3.90 |
| 13 | Southern Mississippi | 10 | 39.0 | 326 | 3.90 |