2021 Conference USA Leaders Interceptions - Games vs. Conference Teams Only through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Western Kentucky | 9 | 18 | 180 | 2 | 2.00 |
| 2 | Rice | 8 | 11 | 45 | 0 | 1.38 |
| 3 | Middle Tennessee | 8 | 10 | 208 | 2 | 1.25 |
| 3 | UTSA | 9 | 10 | 194 | 3 | 1.11 |
| 5 | Southern Mississippi | 8 | 9 | 124 | 3 | 1.13 |
| 6 | Florida Atlantic | 8 | 8 | 144 | 1 | 1.00 |
| 7 | UAB | 8 | 7 | 136 | 1 | 0.88 |
| 7 | Old Dominion | 8 | 7 | 119 | 1 | 0.88 |
| 7 | Marshall | 8 | 7 | 93 | 0 | 0.88 |
| 7 | Charlotte | 8 | 7 | 44 | 2 | 0.88 |
| 11 | Louisiana Tech | 8 | 6 | 114 | 0 | 0.75 |
| 11 | UTEP | 8 | 6 | 4 | 0 | 0.75 |
| 13 | North Texas | 8 | 3 | 98 | 0 | 0.38 |
| 14 | Florida International | 8 | 2 | 0 | 0 | 0.25 |