2021 Conference USA Leaders Interceptions - Games Won Only through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Western Kentucky | 9 | 20 | 208 | 2 | 2.22 |
| 2 | Middle Tennessee | 7 | 12 | 225 | 3 | 1.71 |
| 2 | UTSA | 12 | 12 | 200 | 3 | 1.00 |
| 4 | Rice | 4 | 9 | 19 | 0 | 2.25 |
| 4 | UAB | 9 | 9 | 157 | 1 | 1.00 |
| 6 | Florida Atlantic | 5 | 8 | 71 | 1 | 1.60 |
| 6 | Marshall | 7 | 8 | 128 | 0 | 1.14 |
| 8 | UTEP | 7 | 7 | 50 | 0 | 1.00 |
| 9 | Southern Mississippi | 3 | 5 | 12 | 1 | 1.67 |
| 10 | Old Dominion | 6 | 4 | 88 | 1 | 0.67 |
| 11 | Louisiana Tech | 3 | 3 | 62 | 1 | 1.00 |
| 11 | North Texas | 6 | 3 | 75 | 0 | 0.50 |
| 13 | Charlotte | 5 | 2 | 41 | 1 | 0.40 |