2021 Big 12 Conference Leaders Passing - Games on the Road/Neutral Site Only through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brock Purdy | Iowa State | SR | QB | 7 | 231 | 166 | 71.9 | 1785 | 7.7 | 11 | 5 | 148.15 | 33.0 | 255.0 |
| 2 | Jarret Doege | WVU | SR | QB | 7 | 225 | 146 | 64.9 | 1509 | 6.7 | 7 | 8 | 124.39 | 32.1 | 215.6 |
| 3 | Spencer Sanders | Okla St | JR | QB | 7 | 235 | 145 | 61.7 | 1526 | 6.5 | 11 | 6 | 126.59 | 33.6 | 218.0 |
| 4 | Caleb Williams | Oklahoma | FR | QB | 6 | 130 | 82 | 63.1 | 1044 | 8.0 | 10 | 3 | 151.30 | 21.7 | 174.0 |
| 5 | Gerry Bohanon | Baylor | JR | QB | 6 | 126 | 77 | 61.1 | 920 | 7.3 | 7 | 3 | 136.02 | 21.0 | 153.3 |
| 6 | Skylar Thompson | Kansas St | SR | QB | 4 | 96 | 73 | 76.0 | 953 | 9.9 | 5 | 1 | 174.54 | 24.0 | 238.3 |
| 7 | Casey Thompson | Texas | JR | QB | 6 | 122 | 66 | 54.1 | 898 | 7.4 | 8 | 3 | 132.65 | 20.3 | 149.7 |
| 8 | Henry Colombi | Texas Tech | SR | QB | 4 | 90 | 62 | 68.9 | 791 | 8.8 | 5 | 3 | 154.38 | 22.5 | 197.8 |
| 9 | Max Duggan | TCU | JR | QB | 4 | 79 | 52 | 65.8 | 739 | 9.4 | 7 | 1 | 171.10 | 19.8 | 184.8 |
| 9 | Donovan Smith | Texas Tech | FR | QB | 6 | 79 | 52 | 65.8 | 783 | 9.9 | 4 | 1 | 163.25 | 13.2 | 130.5 |
| 11 | Jalon Daniels | Kansas | SO | QB | 3 | 65 | 46 | 70.8 | 506 | 7.8 | 5 | 1 | 158.46 | 21.7 | 168.7 |
| 12 | Jason Bean | Kansas | JR | QB | 5 | 86 | 44 | 51.2 | 642 | 7.5 | 2 | 5 | 109.92 | 17.2 | 128.4 |
| 13 | Blake Shapen | Baylor | FR | QB | 3 | 49 | 39 | 79.6 | 317 | 6.5 | 3 | 0 | 154.13 | 16.3 | 105.7 |
| 14 | Spencer Rattler | Oklahoma | SO | QB | 3 | 46 | 34 | 73.9 | 390 | 8.5 | 2 | 2 | 150.78 | 15.3 | 130.0 |
| 15 | Hudson Card | Texas | FR | QB | 3 | 54 | 32 | 59.3 | 285 | 5.3 | 2 | 0 | 115.82 | 18.0 | 95.0 |
| 16 | Tyler Shough | Texas Tech | JR | QB | 2 | 35 | 26 | 74.3 | 299 | 8.5 | 1 | 1 | 149.77 | 17.5 | 149.5 |
| 17 | Chandler Morris | TCU | FR | QB | 2 | 34 | 20 | 58.8 | 236 | 6.9 | 0 | 0 | 117.12 | 17.0 | 118.0 |
| 18 | Will Howard | Kansas St | SO | QB | 4 | 28 | 15 | 53.6 | 128 | 4.6 | 0 | 0 | 91.97 | 7.0 | 32.0 |
| 19 | Jaren Lewis | Kansas St | SO | QB | 1 | 19 | 10 | 52.6 | 148 | 7.8 | 1 | 1 | 124.90 | 19.0 | 148.0 |
| 20 | Garrett Greene | WVU | FR | QB | 5 | 12 | 9 | 75.0 | 60 | 5.0 | 0 | 0 | 117.00 | 2.4 | 12.0 |
| 21 | Hunter Dekkers | Iowa State | FR | QB | 2 | 15 | 7 | 46.7 | 50 | 3.3 | 1 | 1 | 83.34 | 7.5 | 25.0 |
| 21 | Miles Kendrick | Kansas | SR | QB | 2 | 10 | 7 | 70.0 | 41 | 4.1 | 0 | 1 | 84.44 | 5.0 | 20.5 |
| 23 | Sam Jackson | TCU | FR | QB | 1 | 1 | 1 | 100.0 | 77 | 77.0 | 0 | 0 | 746.80 | 1.0 | 77.0 |
| 23 | Brennan Presley | Okla St | SO | WR | 7 | 2 | 1 | 50.0 | 6 | 3.0 | 0 | 0 | 75.20 | 0.3 | 0.9 |