2021 Big 12 Conference Leaders Scoring Defense - Games vs. Conference Teams Only through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Iowa State | 9 | 28 | 4 | 27 | 0 | 0 | 207 | 23.0 |
| 2 | Oklahoma State | 10 | 19 | 8 | 19 | 0 | 1 | 159 | 15.9 |
| 3 | Kansas | 9 | 52 | 9 | 52 | 0 | 0 | 391 | 43.4 |
| 4 | Oklahoma | 9 | 32 | 10 | 30 | 0 | 0 | 252 | 28.0 |
| 5 | Texas Tech | 9 | 41 | 11 | 40 | 0 | 1 | 321 | 35.7 |
| 6 | TCU | 9 | 44 | 12 | 42 | 0 | 0 | 342 | 38.0 |
| 7 | Baylor | 10 | 22 | 15 | 21 | 0 | 0 | 198 | 19.8 |
| 7 | West Virginia | 9 | 28 | 15 | 26 | 1 | 0 | 241 | 26.8 |
| 9 | Texas | 9 | 38 | 16 | 35 | 2 | 0 | 315 | 35.0 |
| 10 | Kansas State | 9 | 22 | 17 | 21 | 0 | 1 | 206 | 22.9 |